Magic Mushroom Dosage Guide!

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Effects of Shrooms

Psilocybin is the active psychedelic ingredient in psychedelic mushrooms. The threshold dose for feeling the effects from dried mushrooms is typically in the 0.2-0.5g range, though it varies for each individual person. A moderate dose in the 1-2.5g range, taken orally, typically produces effects that last from three to six hours. Psilocybin is about 100 times less potent than LSD and 10 times less potent than mescaline.

When you take psilocybin, your body metabolizes the substance into psilocin, both of which produce the psychedelic effects. Psilocybin and psilocin primarily interact with serotonin receptors in the brain and have an especially high affinity for the 5-HT (serotonin) 2A subtype receptors. In rodents, psilocybin has shown a strong interaction with receptors in hub regions of the brain that integrate sensory experiences. This could explain effects such as synesthesia—the experience of mixing sensory modalities, such as hearing colors or tasting sounds—and altered sensory experiences during mushroom trips.

Effects by Dose

NOTE: The effects listed below aren’t meant to be comprehensive, particularly at the lower dose ranges. They may be subject to change as more reliable, widely representative data become available.

These dose ranges are for Psilocybe cubensis mushrooms. They may apply to other psilocybin-containing species, but some (e.g. P. semilanceata) are  more potent on average.

Microdose (0.05-0.25 g)

A microdose is a sub-perceptual (unnoticeable) dose, which many people incorporate into their weekly routines. The idea behind this is to enhance levels of creativity, energy, and focus, and decrease levels of stress, anxiety, and emotional instability. Find out more in our microdosing guide. Common effects include:

  • Mood enhancement
  • Decreased stress
  • Emotional stability
  • Mindfulness, presence, and peace
  • Openness and self-forgiveness
  • Conversational fluidity
  • Alleviation of persistent conditions such as depression, anxiety, ADD/ADHD, and PTSD
  • Increased motivation (e.g. to make positive lifestyle changes)
  • Increased flow states
  • Clearer, more connected thinking
  • Improved memory
  • Increased creativity
  • Easier meditation
  • Enhanced athletic endurance
  • Increased energy overall (without anxiety or a subsequent crash)
  • Slight amplification of mood, positive or negative
  • Possible manic states
  • Potentially increased neuroticism

Mini-dose (0.25-0.75 g)

While a proper microdose shouldn’t be felt, a mini-dose of psilocybin takes you just above the perceptual threshold—but it’s not a full-blown trip. As one of our community members put it, a mini-dose gives you “that total expansion of being, total freeflow feeling” without losing touch with your surroundings. Common effects include:

  • Mood enhancement, mild euphoria or excitement
  • Mindfulness, presence, and peace
  • Openness and self-forgiveness
  • Introspective insights
  • Alleviation of persistent conditions such as depression, anxiety, ADD/ADHD, and PTSD
  • Increased motivation (e.g. to make positive lifestyle changes)
  • Increased flow states
  • Clearer, more connected thinking
  • Enhanced senses
  • Easier meditation
  • Increased enjoyment of physical activity and everyday tasks
  • Preference for introspection over socializing
  • Increased sensitivity to light
  • Very mild visuals, if any
  • Possible manic states
  • Difficulty focusing or thought loops
  • Difficulty with some cognitive tasks
  • Anxiety, agitation, or restlessness
  • Difficulty or discomfort socializing

Museum dose (0.5-1.5 g)

The effects of psilocybin are more apparent with a museum dose than with a mini-dose, but a museum dose still won’t give you a full psychedelic experience. The name “museum dose,” coined by the biochemist and pharmacologist  Dr. Alexander Shulgin, refers to the fact that on this dose, you can still participate in public activities (such as viewing paintings in a museum) without attracting attention. Common effects include:

  • Mood enhancement, euphoria or excitement
  • Mild to moderate visuals (e.g. “breathing” environments)
  • Increased empathy
  • Conversational fluidity
  • Introspection
  • Increased flow states
  • Enhanced senses
  • Enhanced appreciation for music, art, etc.
  • Increased creativity
  • Amplification of mood, positive or negative
  • Altered perception of sound
  • Time dilation or contraction (time passing more slowly or quickly)
  • Increased sensitivity to light
  • Pupil dilation
  • Difficulty focusing or thought loops
  • Difficulty or discomfort socializing
  • Frustration at dosage (the “no man’s land”)

Moderate dose (2-3.5 g)

This is where the full psychedelic experience begins. You’ll likely see visual hallucinations, including patterns and fractals, and things like time and depth perception will be distorted. But with this dose, you’re still able to grasp your surroundings—they’ll just be highly altered. Common effects include:

  • Life-changing introspective or philosophical insights
  • Increased flow of ideas
  • Enhanced appreciation for music, art, etc.
  • Finding otherwise mundane things funny or interesting
  • Clear come-up, peak, and come-down
  • Amplification of emotions, whether good or bad
  • Open- and closed-eye visuals (e.g. patterns, auras)
  • Synesthesia
  • Sensitivity to light
  • Compulsive yawning
  • Disorientation
  • Fear and anxiety (“bad trip” experiences)
  • Difficulty with cognitive tasks
  • Dizziness
  • Nausea

Megadose (5+ g)

A megadose brings on a total loss of connection with reality. This is where you’ll experience intense hallucinations, as well as ego death, mystical experiences, and deep introspection. Common effects include:

  • Mystical experience and intense feelings of wonder
  • Life-changing introspective or philosophical insights
  • Ego death
  • Very strong open- and closed-eye visions (e.g. memories coming to life)
  • Synesthesia
  • Time becoming meaningless
  • Disorientation
  • Compromised motor functions (sitter recommended!)
  • Strong fear and anxiety (extreme “bad trip” experiences)
  • Extreme difficulty with cognitive tasks
  • Dizziness
  • Nausea

Interactions With Other Drugs

So far, not much data exists around psilocybin’s interaction with other drugs, whether good or bad, but it’s best to be intentional and err on the side of caution when mixing any two substances together. Here’s what we do know.

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